Email this article Gialiniziruyushchaya trabekulyarnaya opukhol' shchitovidnoy zhelezy
- Authors: Mal'kov PG1, Morozova MA1, Grinevich VN1, Abrosimov AY.1, Minasyan AM1
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- Issue: Vol 14, No 1 (2009)
- Pages: 46-48
- Section: Articles
- URL: https://rjonco.com/1028-9984/article/view/39838
- DOI: https://doi.org/10.17816/onco39838
- ID: 39838
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Abstract
The paper describes a case of thyroid hyalinizing trabecular tumor in a 55-year-old woman. Cytological examination of her fine-needle biopsy specimen showed separately lying tumor cells with intracellular cytoplasmic inclusions. Its cytological study determined the trabeculoalveolar structures formed by tumor cells, the intercellular space exhibited a homogenous eosinophilic matter that yielded a positive Schick's test, laminated calcinates that mimick psammoma bodies. Immunophenotyping of the neoplasm revealed a positive reaction with antibodies to thyroglobulin, a negative reaction to galectin-3 and cytokeratin-19, and membrane Ki-67 expression, which suggests the low malignancy potential.
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References
- Carney J. A., Ryan J., Goellner J. R. // Am. J. Surg. Pathol. - 1987. - Vol. 11, N 8. - P. 583-591.
- Gonzalez-Campora R., Fuentes-Vaamonde E., Hevia-Vazquez A. et al. // Ultrastruct. Pathol. - 1998. - Vol. 22, N 1. - P. 39- 46.
- Katoh R., Jasani B., Williams E. D. // Histopathology. - 1989. - Vol. 15. - P. 211-224.
- McCluggage W. G., Sloan J. M. // Histopathology. - 1996. - Vol. 28. - P. 357-362.
- Molberg K., Albors-Saavedra J. // Hum. Pathol. - 1994. - Vol. 25. - P. 192-197.
- Pathology and Genetics of Tumours of Endocrine Organs. World Health Organization Classification of Tumours / Eds R. A. DeLellis et al. - Lyon, 2004. - P. 104-105.
- Rosai J. Ackerman's Surgical Pathology. - 9-th Ed. - St. Louis, 2004. - Vol. 1. - P. 515-594.
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