Russian Journal of OncologyRussian Journal of Oncology1028-99842412-9119Eco-Vector4016710.17816/onco40167Research ArticleClinical morphological features of a hereditary breast cancer and their influence on the treatmentShoykhetYa. N-LazarevA. FThe Altai Branch of N.N. Blokhin Russian Cancer Research Center-GofmanAlina A.MDalina-barnaul@mail.ruZadontsevaN. S-LazarevaD. G.-Altai State Medical UniversityN.N. Blokhin Russian Cancer Research CenterThe Altai Regional Oncological ClinicAltai Regional Oncological Clinic151020152054722072020Copyright © 2015, Eco-Vector2015Objective - to examine the clinical and morphological characteristics of hereditary breast cancer and their impact on the nature of the treatment. Material and methods. A comparative study between women with hereditary forms of breast cancer and sporadic breast cancer. The work is based on information about 727 women. The women were divided into two groups: primary, including 377 women with hereditary forms of breast cancer and a comparison to include 350 women with sporadic breast cancer. Results. Statistically significant differences were obtained by the nature, location, growth receptor status of the tumor site, presence of regional lymph node metastasis by special treatment.hereditary breast cancersporadic breast cancermalignancyнаследственный рак молочной железыспорадический рак молочной железыстепень злокачественности[Имянитов Е.Н. Наследственный рак молочной железы. Практическая онкология. 2010; 11 (4): 258-66.][Любченко Л.Н., Гарькавцева Р.Ф. Клинико-генетическая гетерогенность семейного рака молочной железы. Современная онкология. 2004; 6 (2): 67-9.][Лазарев А.Ф., Задонцева Н.С., Гофман А.А. Наследственный рак молочной железы. Российский онкологический журнал. 2014; 2: 40-6.][Наследственные формы рака молочной железы и/или яичников: прогноз, тактика лечения и профилактика. VII Российская онкологическая конференция. http://www.rosoncoweb.ru/library/congress/ru/07/45.php][Айламазян Э.К. Современные подходы к профилактике рака молочной железы у больных пролиферативными процессами репродуктивной системы. Медицинский академический журнал. 2006; 6 (3): 16-27.][Имянитов Е.Н., Хансон К.П. Молекулярная онкология: клинические аспекты. СПб.: Медицина; 2007.][Marchetty P., Di Ricco C.Z., Ricevuto E. et al. Reducing breast cancer incidence in familial breast cancer: overlooking the present panorama. Ann. Oncol. 2004; 15 (1): 127-34.]