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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="research-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Russian Journal of Oncology</journal-id><journal-title-group><journal-title xml:lang="en">Russian Journal of Oncology</journal-title><trans-title-group xml:lang="ru"><trans-title>Российский онкологический журнал</trans-title></trans-title-group></journal-title-group><issn publication-format="print">1028-9984</issn><issn publication-format="electronic">2412-9119</issn><publisher><publisher-name xml:lang="en">Eco-Vector</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">42969</article-id><article-id pub-id-type="doi">10.18821/1028-9984-2018-23-2-79-81</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Articles</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Статьи</subject></subj-group><subj-group subj-group-type="article-type"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">MULTIPLE PRIMARY TUMORS IN CHRONIC LEUKEMIA AND GENERALIZED LYMPHOMAS</article-title><trans-title-group xml:lang="ru"><trans-title>ПЕРВИЧНО-МНОЖЕСТВЕННЫЕ ОПУХОЛИ ПРИ ХРОНИЧЕСКИХ И ГЕНЕРАЛИЗОВАННЫХ ЛИМФОМАХ</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Buevich</surname><given-names>E. I</given-names></name><name xml:lang="ru"><surname>Буевич</surname><given-names>Е. И</given-names></name></name-alternatives><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Kotovshchikova</surname><given-names>Elena F.</given-names></name><name xml:lang="ru"><surname>Котовщикова</surname><given-names>Елена Фёдоровна</given-names></name></name-alternatives><bio xml:lang="en"><p>MD, PhD, Professor of the Department of Propaedeutics of Internal Diseases, Barnaul, 656038, Russian Federation</p></bio><bio xml:lang="ru"><p>д-р мед. наук, проф. кафедры пропедевтики внутренних болезней им. проф. З.С. Баркагана Алтайского государственного медицинского университета</p></bio><email>kotov-l@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Lazarev</surname><given-names>A. F</given-names></name><name xml:lang="ru"><surname>Лазарев</surname><given-names>А. Ф</given-names></name></name-alternatives><xref ref-type="aff" rid="aff1"/><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Ganov</surname><given-names>D. I</given-names></name><name xml:lang="ru"><surname>Ганов</surname><given-names>Д. И</given-names></name></name-alternatives><xref ref-type="aff" rid="aff2"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">Altay State Medical University</institution></aff><aff><institution xml:lang="ru">ФГБОУ ВПО «Алтайский государственный медицинский университет» Минздрава России</institution></aff></aff-alternatives><aff-alternatives id="aff2"><aff><institution xml:lang="en">Altay branch of the National Medical Research Center of Oncology</institution></aff><aff><institution xml:lang="ru">Алтайский филиал ФГБУ «НМИЦ онкологии им. Н.Н. Блохина» Минздрава России</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2018-04-15" publication-format="electronic"><day>15</day><month>04</month><year>2018</year></pub-date><volume>23</volume><issue>2</issue><issue-title xml:lang="en">VOL 23, NO2 (2018)</issue-title><issue-title xml:lang="ru">ТОМ 23, №2 (2018)</issue-title><fpage>79</fpage><lpage>81</lpage><history><date date-type="received" iso-8601-date="2020-08-24"><day>24</day><month>08</month><year>2020</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2018, Eco-Vector</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2018, ООО "Эко-Вектор"</copyright-statement><copyright-year>2018</copyright-year><copyright-holder xml:lang="en">Eco-Vector</copyright-holder><copyright-holder xml:lang="ru">ООО "Эко-Вектор"</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/></permissions><self-uri xlink:href="https://rjonco.com/1028-9984/article/view/42969">https://rjonco.com/1028-9984/article/view/42969</self-uri><abstract xml:lang="en"><p>There are presented results of the analysis of case histories of 418 patients with generalized lymphomas and chronic leukemia, among whom 49 patients had information about multiple primary cancers. Among these patients, 37 were diagnosed as generalized lymphoma, 8 - multiple myeloma and 4 - chronic myelomonocytic leukemia. Most often hemoblastosis combined with skin cancer (17 patients), bowel cancer (11 patients) and lung cancer (9 patients). 3 patients had hemoblastosis combination with prostate, as well as kidney, stomach, and thyroid malignant diseases. Among all cases, 44 patients had two multiple primary tumors, 4 patients had three tumors. In this work, the analysis of patients is given according to the age-gender structure, time of the onset of the development of tumors. As an example, the short information about 4 patients with hematological malignancies in combination with other tumors is given.</p></abstract><trans-abstract xml:lang="ru"><p>Представлены результаты анализа по историям болезни 418 пациентов с генерализованными лимфомами и хроническими лейкозами, из них у 49 больных была информация о первично-множественных опухолях. Среди этих пациентов у 37 диагностирована генерализованная лимфома, у 8 - миеломная болезнь и у 4 - хронический миеломоноцитарный лейкоз. Наиболее часто рассматриваемые гемобластозы сочетались с раком кожи (17 больных), кишечника (11 больных), лёгкого (9 больных). По три пациента имели сочетание гемобластоза со злокачественными заболеваниями предстательной железы, почки, желудка, щитовидной железы. Среди всех больных по две первично-множественные опухоли были у 44, по три - у четырёх и четыре - у одной больной. В работе проанализированы возрастно-половой состав пациентов, время появления опухолей. В качестве примера дана краткая информация о четырёх больных гемобластозами в сочетании с другими опухолями.</p></trans-abstract><kwd-group xml:lang="en"><kwd>generalized lymphomas</kwd><kwd>chronic leukemia</kwd><kwd>cancer</kwd><kwd>multiple primary cancers</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>генерализованная лимфома</kwd><kwd>хронический лейкоз</kwd><kwd>рак</kwd><kwd>первично-множественные опухоли</kwd></kwd-group></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Soerjomataram I., Coebergh J.W. Epidemiology of multiple primary cancers. Methods Mol. Biol. 2009; 471: 85-105. DOI: 10.1007/978-1-59745-416-2_5</mixed-citation></ref><ref id="B2"><label>2.</label><mixed-citation>Zhao J., Tan Y., Wu Y., Zhao W., Wu J., Ji M., Shi L., Jiang J., Wu C. A rare case of eight multiple primary malignant neoplasms in a female patient: A case report and review of the literature. Oncol. Lett. 2015; 9(2): 587-90. 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