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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="research-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Russian Journal of Oncology</journal-id><journal-title-group><journal-title xml:lang="en">Russian Journal of Oncology</journal-title><trans-title-group xml:lang="ru"><trans-title>Российский онкологический журнал</trans-title></trans-title-group></journal-title-group><issn publication-format="print">1028-9984</issn><issn publication-format="electronic">2412-9119</issn><publisher><publisher-name xml:lang="en">Eco-Vector</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">70322</article-id><article-id pub-id-type="doi">10.17816/1028-9984-2020-25-5-181-185</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Case Reports</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Клинические случаи</subject></subj-group><subj-group subj-group-type="article-type"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">Giant condiloma of Bushke–Löwenstein: a clinical case</article-title><trans-title-group xml:lang="ru"><trans-title>Гигантская кондилома Бушке-Левенштейна</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Menshikov</surname><given-names>Konstantin V.</given-names></name><name xml:lang="ru"><surname>Меньшиков</surname><given-names>Константин Викторович</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>MD, PhD, oncologist of the Department of Chemotherapy of the Republican Clinical Oncological Dispensary, 450054, Ufa, Russian Federation, Associate Professor of the Department of Oncology with courses oncology and pathological anatomy, Bashkir State Medical University, 450008, Ufa, Russian Federation</p></bio><bio xml:lang="ru"><p>к.м.н., врач-онколог отдела химиотерапии ГАУЗ «Республиканский клинический онкологический диспансер» Министерства здравоохранения Республики Башкортостан, Россия, Республика Башкортостан, г. Уфа, пр. Октября, 73/1, 450054, доцент кафедры онкологии с курсами онкологии и патологической анатомии ФГБОУ ВО «Башкирский государственный медицинский университет» Министерства здравоохранения Российской Федерации</p></bio><email>kmenshikov80@bk.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Lipatov</surname><given-names>O. N.</given-names></name><name xml:lang="ru"><surname>Липатов</surname><given-names>О. Н.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><email>kmenshikov80@bk.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Nasyrova</surname><given-names>S. F.</given-names></name><name xml:lang="ru"><surname>Насырова</surname><given-names>С. Ф.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><email>kmenshikov80@bk.ru</email><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">Bashkir State Medical University</institution></aff><aff><institution xml:lang="ru">ФГБОУ ВО «Башкирский государственный медицинский университет» Министерства здравоохранения Российской Федерации</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2020-10-15" publication-format="electronic"><day>15</day><month>10</month><year>2020</year></pub-date><volume>25</volume><issue>5</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>181</fpage><lpage>185</lpage><history><date date-type="received" iso-8601-date="2021-05-07"><day>07</day><month>05</month><year>2021</year></date><date date-type="accepted" iso-8601-date="2021-05-07"><day>07</day><month>05</month><year>2021</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2021, Eco-Vector</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2021, ООО "Эко-Вектор"</copyright-statement><copyright-year>2021</copyright-year><copyright-holder xml:lang="en">Eco-Vector</copyright-holder><copyright-holder xml:lang="ru">ООО "Эко-Вектор"</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/" start_date="2024-05-14"/></permissions><self-uri xlink:href="https://rjonco.com/1028-9984/article/view/70322">https://rjonco.com/1028-9984/article/view/70322</self-uri><abstract xml:lang="en"><p>Giant condyloma Buschke-Levenshtein is a large, exophytic, slow-growing, benign, warty lesion of the anogenital region. The cause of this pathology is infection with the human papillomavirus, mainly of the 6th or 11th type. The pathogenesis of giant genital warts is not well understood, and it is often considered an intermediate link between acute warts and squamous cell carcinoma. The frequency of occurrence in the general population is about 0.1%, which indicates the rarity of this pathology. The giant condyloma Buschke-Löwenstein was first described by the authors Buschke and Löwenstein in 1925. Currently, the literature contains descriptions of mostly single observations of patients with this pathology. The main method of treatment for giant condyloma Buschke-Levenshtein is surgical, the task of which is a wide excision of the tumor within healthy tissues. We present a clinical observation of a patient with a giant condyloma Buschke-Levenshtein. a 36-year-old patient underwent surgical treatment - removal of a large perineal tumor. At the time of surgery, the size of the tumor was about 25 × 15 cm. The patient underwent surgical treatment without complications, healing by primary intention. Within six months after the operation, no recurrence of the disease was detected. Thus, surgical treatment of such tumors is the only method that can count on the patient being cured.</p></abstract><trans-abstract xml:lang="ru"><p>Гигантская кондилома Бушке-Левенштейна – это большое, экзофитное, медленнорастущее, доброкачественное, бородавчатое поражение аногенитальной области. Причиной данной патологии является инфицирование вирусом папилломы человека, преимущественно 6-го или 11-го типа. Патогенез гигантской остроконечной кондиломы изучен недостаточно, еë часто считают промежуточным звеном между острой кондиломой и плоскоклеточным раком. Частота встречаемости в общей популяции составляет около 0,1%, что говорит о редкости данной патологии. Гигантская кондилома Бушке-Левенштейна впервые описана авторами Buschke и Löwenstein в 1925 г. В настоящее время в литературе встречаются описания в основном единичных наблюдений пациентов с этой патологией. Основным методом лечения гигантской кондиломы Бушке-Левенштейна является хирургический, задача которого – широкое иссечение опухоли в пределах здоровых тканей. Мы приводим клиническое наблюдение 36-летней пациентки с гигантской кондиломой Бушке-Левенштейна, которой произведено хирургическое лечение – удаление опухоли промежности больших размеров. На момент операции размеры опухоли составляли 25 × 15 см. Хирургическое лечение пациентка перенесла без осложнений, заживление первичным натяжением. В течение полугода с момента операции рецидива заболевания не выявлено. Таким образом, хирургическое лечение подобных опухолей – единственный метод, позволяющий рассчитывать на излечение пациента.</p></trans-abstract><kwd-group xml:lang="en"><kwd>giant condyloma Buschke-Levenshtein</kwd><kwd>surgical treatment</kwd><kwd>vulvectomy</kwd><kwd>papillomatosis</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>гигантская кондилома Бушке-Левенштейна</kwd><kwd>хирургическое лечение</kwd><kwd>вульвэктомия</kwd><kwd>папилломатоз</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><citation-alternatives><mixed-citation xml:lang="en">Sandhu R, Min Z, Bhanot N. A gigantic anogenital lesion: buschke-lowenstein tumor. Case Rep Dermatol Med. 2014;650714. DOI: 10.1155/2014/650714. Epub 2014 Nov 6.</mixed-citation><mixed-citation xml:lang="ru">Sandhu R., Min Z., Bhanot N. A gigantic anogenital lesion: buschke-lowenstein tumor. Case Rep Dermatol Med. 2014. 650714. DOI: 10.1155/2014/650714. 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