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CLINICAL SEMIOTICS AND SURGICAL PREOPERATIVE DIAGNOSIS OF STAGE-I BREAST CANCER

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1. Title Title of document CLINICAL SEMIOTICS AND SURGICAL PREOPERATIVE DIAGNOSIS OF STAGE-I BREAST CANCER
2. Creator Author's name, affiliation, country I. V Kolyadina; Russian Medical Academy of Postgraduate Education; N.N. Blokhin Russian Cancer Research Center under the Russian Academy of Medical Sciences
2. Creator Author's name, affiliation, country D. V Komov; N.N. Blokhin Russian Cancer Research Center under the Russian Academy of Medical Sciences
2. Creator Author's name, affiliation, country I. V Poddubnaya; Russian Medical Academy of Postgraduate Education; N.N. Blokhin Russian Cancer Research Center under the Russian Academy of Medical Sciences
2. Creator Author's name, affiliation, country T. Yu Danzanova; N.N. Blokhin Russian Cancer Research Center under the Russian Academy of Medical Sciences
2. Creator Author's name, affiliation, country L. A Kostyakova; N.N. Blokhin Russian Cancer Research Center under the Russian Academy of Medical Sciences
2. Creator Author's name, affiliation, country G. T Sinyukova; N.N. Blokhin Russian Cancer Research Center under the Russian Academy of Medical Sciences
2. Creator Author's name, affiliation, country S. M Banov; Clinic of Russian Medical Academy of Postgraduate Education
3. Subject Discipline(s)
3. Subject Keyword(s) Screening breast cancer; clinical symptoms of breast cancer I-stage; fine-needle biopsy (FNAB) and corebiopsy with USG and MG control
4. Description Abstract Screening tumors of breast are detected by instrumental methods of diagnosis, such as mammography (MG), ultrasonography (USG) and magnetic resonance imaging (MRI) only; typically have a size to 2.0 cm (T1) and need support (MG or USG control) at biopsy for morphological study. In the present study the clinical symptoms were analyzed using a large clinical data (1,347 patients with stage-I breast cancer), the rate of screening tumors and the possibility of pre-surgical biopsy of these tumors. The proportion of screening cancer, identified by instrumental methods of diagnosis was only 12.8%, which means the insufficient level of screening programs for all age groups women. Screening methods had the maximum diagnostic value in microcarcinomas (tumors less than 5 mm) which had no clinical symptoms and almost non-palpable. Young patients (<40 years) found breast cancer themselves and went to oncologist (more than 90% of cases; patients 50 years older - in 78% cases, p <0,05). Surgical biopsy with USG or MG control has improved the effectiveness of a biopsy from 74.4% (without instrumental control) to 93%; core-biopsy of tumors has helped to determinate of morphological diagnosis more exactly and plan treatment algorithm in these patients.
5. Publisher Organizing agency, location Eco-Vector
6. Contributor Sponsor(s)
7. Date (DD-MM-YYYY) 15.08.2013
8. Type Status & genre Peer-reviewed Article
8. Type Type Research Article
9. Format File format
10. Identifier Uniform Resource Identifier https://rjonco.com/1028-9984/article/view/39997
10. Identifier Digital Object Identifier (DOI) 10.17816/onco39997
10. Identifier Digital Object Identifier (DOI) (PDF (Rus)) 10.17816/onco39997-26546
11. Source Title; vol., no. (year) Russian Journal of Oncology; Vol 18, No 4 (2013)
12. Language English=en ru
13. Relation Supp. Files
14. Coverage Geo-spatial location, chronological period, research sample (gender, age, etc.)
15. Rights Copyright and permissions Copyright (c) 2013 Eco-Vector