Relationship between mortality from diseases of the circulatory system with the consumption of alcoholic beverages

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The purpose of the study is to identify the relationship between total mortality and due to diseases of the circulatory system (CSD) with indicators of sales and consumption of alcoholic beverages in the Republic of Mari El.

Material and methods. The analysis includes data from official federal and regional statistics on alcohol sales, total and CSD mortality. Alcohol consumption was calculated according to the methodological recommendations of the Russian Ministry of Health. To evaluate the time series, we calculated the coefficient of determination, the median with a 95% confidence interval, the Mann–Whitney test, and the Spearman correlation coefficient with a time lag.

Results. Over 2000–2018 mortality due to CSD in the Republic of Mari El decreased, not differing from the average Russian indicator in terms of level and trend. In the region, per capita sales of alcoholic beverages (from 4.4 to 8.1 liters) were significantly lower than estimated alcohol consumption (from 10.9 to 21.3 liters). A strong relationship between CSD associated mortality was established with per capita estimated consumption of strong alcohol (r = 0.97–0.5 with a lag of 0 to 6 years) and sales of vodka per capita (r = 0.77–0.48 with a lag of 0 up to 3 years), with a high correlation among the working-age population in men (r = 0.82–0.64 with a lag of 0 to 4 years) and a long-term one in women (r = 0.72–0.48 with a lag of 0 up to 5 years).

Research limitations. The study has regional (Republic of Mari El) restrictions.

Conclusion. CSD associated mortality rates are statistically significantly correlated with the sale and consumption of alcoholic beverages with a delayed effect. Therefore, one of the ways to reduce mortality may be measures to reduce alcohol consumption.

Compliance with ethical standards. The study does not require the submission of the opinion of the biomedical ethics committee.

Acknowledgment. The study had no sponsorship.

Conflict of interest. The author declares no conflict of interest. 

Received: February 27, 2021 
Accepted: May 14, 2021
Published: February 28, 2023

Sobre autores

Denis Loskutov

Kazan (Volga region) Federal University

Autor responsável pela correspondência
Email: loskutov-denis@mail.ru
ORCID ID: 0000-0001-7600-0769

MD, PhD, freelance researcher, Institute of fundamental medicine and biology of the Kazan (Volga region) Federal University, Kazan, 420138, Russian Federation.

e-mail: loskutov-denis@mail.ru

Rússia

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