Synthesis of Reactive Pegylated Indocyanine Dyes

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Resumo

Synthesis was carried out with the selection of conditions for the isolation and purification of fluorescently labeled polyethylene glycol with a reactive carboxyl group for labeling biomolecules. Pegylated nucleotides, which are part of drugs, allow targeted delivery to the target organ, prolong the half-life, reduce immunogenicity and increase stability.

Sobre autores

V. Shershov

Engelhardt Institute of Molecular Biology, Russian Academy of Sciences

Moscow, Russia

V. Kuznetsova

Engelhardt Institute of Molecular Biology, Russian Academy of Sciences

Email: kuzneimb@gmail.com
Moscow, Russia

G. Shtylev

Engelhardt Institute of Molecular Biology, Russian Academy of Sciences

Moscow, Russia

I. Shishkin

Engelhardt Institute of Molecular Biology, Russian Academy of Sciences

Moscow, Russia

R. Miftahov

Engelhardt Institute of Molecular Biology, Russian Academy of Sciences

Moscow, Russia

V. Butvilovskaya

Engelhardt Institute of Molecular Biology, Russian Academy of Sciences

Moscow, Russia

I. Grechishnikova

Engelhardt Institute of Molecular Biology, Russian Academy of Sciences

Moscow, Russia

A. Stomahin

Engelhardt Institute of Molecular Biology, Russian Academy of Sciences

Moscow, Russia

O. Zasedateleva

Engelhardt Institute of Molecular Biology, Russian Academy of Sciences

Moscow, Russia

A. Chudinov

Engelhardt Institute of Molecular Biology, Russian Academy of Sciences

Moscow, Russia

Bibliografia

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