Study of reaction of ( E )-(3-aryl-3-oxoprop-1-en-1-yl)triphenylphosphonium bromides with 2-aminopyridine

R. J. Khachikyan; Хачикян Рая Джаановна; K. K. Harutyunyan; Арутюнян Карина Кароевна; A. G. Ayvazyan; Айвазян Армен Григорьевич; Z. G. Hovakimyan; Овакимян Заруи Грантовна

doi:10.31857/S0514749225020109

Study of reaction of (E)-(3-aryl-3-oxoprop-1-en-1-yl)triphenylphosphonium bromides with 2-aminopyridine

作者: Khachikyan R.J.¹, Harutyunyan K.K.¹, Ayvazyan A.G.¹, Hovakimyan Z.G.¹
隶属关系:
1. Institute of Organic Chemistry, Scientific and Technological Center of Organic and Pharmaceutical Chemistry, National Academy of Sciences of Armenia
期: 卷 61, 编号 2 (2025)
页面: 197-202
栏目: Articles
URL: https://rjonco.com/0514-7492/article/view/684333
DOI: https://doi.org/10.31857/S0514749225020109
EDN: https://elibrary.ru/DHFDTU
ID: 684333

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详细

(E)-(3-Aryl-3-oxoprop-1-en-1-yl)triphenylphosphoniumbromides react with 2-aminopyridine to form [(2-aryl-3-imidazo-[1,2-α-]pyridin-3-yl)methyl]triphenylphosphoniumbromides. An alternative scheme of the reactions is proposed, including an initial attack of the nucleophile on the carbonyl group.

关键词

2-aminopyridine, β-aroylvinyltriphenylphosphoniumbromide, biological activity, heterocyclization, nucleophile

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作者简介

R. Khachikyan

Institute of Organic Chemistry, Scientific and Technological Center of Organic and Pharmaceutical Chemistry, National Academy of Sciences of Armenia

编辑信件的主要联系方式.
Email: khachikyanraya@gmail.com
ORCID iD: 0009-0006-2014-7861
亚美尼亚, prosp. Azatutyan, 26, Yerevan, 0014

K. Harutyunyan

Institute of Organic Chemistry, Scientific and Technological Center of Organic and Pharmaceutical Chemistry, National Academy of Sciences of Armenia

Email: khachikyanraya@gmail.com
ORCID iD: 0000-0002-3274-1239
亚美尼亚, prosp. Azatutyan, 26, Yerevan, 0014

A. Ayvazyan

Institute of Organic Chemistry, Scientific and Technological Center of Organic and Pharmaceutical Chemistry, National Academy of Sciences of Armenia

Email: khachikyanraya@gmail.com
ORCID iD: 0000-0002-3224-0549
亚美尼亚, prosp. Azatutyan, 26, Yerevan, 0014

Z. Hovakimyan

Institute of Organic Chemistry, Scientific and Technological Center of Organic and Pharmaceutical Chemistry, National Academy of Sciences of Armenia

Email: khachikyanraya@gmail.com
ORCID iD: 0009-0000-1604-5834
俄罗斯联邦, prosp. Azatutyan, 26, Yerevan, 0014

参考

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