EXPERIMENTAL STUDIES OF THE COMBINED ACTION OF MULTICOMPONENT CHEMICAL AEROSOL AND LOW TEMPERATURE

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Abstract

The comparative complex cytomorphological study of the combined action of low temperature and mixed aerosol containing sulfuric compounds has been conducted. The experiments were made on animals adapted and not adapted to cold action. The analysis of the obtained results allows to state that the combined effect of the factors studied has a pronounced effect on the development of disorders in the bronchopulmonary, cardiovascular, and liver systems. The data obtained show unidirectional changes in cytomorphological parameters with changes in the bronchopulmonary system. However, in non-adapted animals, structural and metabolic changes in the lungs, liver, heart and subcutaneous connective tissue were recorded earlier (60 days) than in the adapted ones (120 days).

About the authors

N. I. Nikolaeva

I.M. Sechenov First Moscow State Medical University

Author for correspondence.
Email: nikolayeva@gmail.com

Nikolaeva Natalia Ivanovna 

119991, Moscow

Russian Federation

V. N. Rakitskii

F.F. Erisman Federal Center of Hygiene of Rospotrebnadzor

Email: pesticidi@yandex.ru

Rakitskii Valery Nikolaevich

141014, Mytishchi, Moscow Region

Russian Federation

A. S. Filin

I.M. Sechenov First Moscow State Medical University

Email: andrey.filin@mail.ru

Filin Andrey Sergeevich

119991, Moscow

Russian Federation

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Copyright (c) 2019 Nikolaeva N.I., Rakitskii V.N., Filin A.S.


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