Neoadjuvant chemotherapy using taxanes in the combination treatment of non-small cell lung cancer

S V Miller; Миллер С В; S A Tuzikov; Тузиков С А; V E Gol'dberg; Гольдберг В Е; A A Zav'yalov; Завьялов А А; T V Polishchuk; Полищук Т В; A Yu Dobrodeev; Добродеев А Ю; E L Yumov; Юмов Е Л; A F Lobykin; Лобыкин А Ф; S V Miller; Miller S V; S A Tuzikov; Tuzikov S A; V E Goldberg; Goldberg V E; A A Zavyalov; Zavyalov A A; T V Polishchuk; Polishchuk T V; A Yu Dobrodeyev; Dobrodeyev A Yu; E L Yumov; Yumov E L; A F Lobykin; Lobykin A F

doi:10.17816/onco39864

Neoadjuvant chemotherapy using taxanes in the combination treatment of non-small cell lung cancer

Authors: Miller SV¹, Tuzikov SA¹, Gol'dberg VE¹, Zav'yalov AA¹, Polishchuk TV¹, Dobrodeev AY.¹, Yumov EL¹, Lobykin AF¹, Miller SV¹, Tuzikov SA¹, Goldberg VE¹, Zavyalov AA¹, Polishchuk TV¹, Dobrodeyev AY.¹, Yumov EL¹, Lobykin AF¹
Affiliations:
Issue: Vol 16, No 5 (2011)
Pages: 4-8
Section: Articles
URL: https://rjonco.com/1028-9984/article/view/39864
DOI: https://doi.org/10.17816/onco39864
ID: 39864

Cite item

Abstract

The results of combination treatment with neoadjuvant chemotherapy using paclitaxel/carboplatin and docetaxel/cisplatin regimens, radical surgery, and 15-Gy intraoperative radiotherapy (IORT) were studied in 105 patients with stage III non-small cell lung cancer. Neoadjuvant chemotherapy resulted in a high immediate response rate (40.2 ± 5.7%). Chemotherapy response is directly correlated with tumor tissue involvement confirmed by histological examination. Preoperative systemic anti-tumor therapy showed a statistically significant increase in relapse-free and overall survivals in patients with locally advanced non-small cell lung cancer.

Keywords

non-small cell lung cancer, surgical treatment, chemotherapy, intraoperative radiation

References

Горбунова В. А., Маренич А. Ф., Пчелин Ю. Ю. // Рос. онкол. журн. - 2007. - № 1. - С. 51-54.
Мардынский Ю. С., Золотков А. Г., Кудрявцев Д. В. // Вопр. онкол. - 2006. - Т. 52, № 5. - С. 499-504.
Мерабишвили В. М. Злокачественные новообразования в мире, России, Санкт-Петербурге. - СПб., 2007.
Трахтенберг А. Х., Колбанов К. И., Вурсол Д. А. // Рос. онкол. журн. - 2007. - № 2. - С. 9-13.
Харченко В. П., Чхиквадзе В. Д., Паньшин Г. А., Гваришвили А. А. Современные технологии в онкологии: Материалы VI Всероссийского съезда онкологов. - М., 2005. - Т. 2. - С. 447.
Calvo F. A., Hoekstra H. G., Lehnert T. // Eur. J. Surg. Oncol. - 2000. - Vol. 26 (suppl.). - P. 3-7.
Martin J., Ginsberg R. J., Venkatraman E. S. et al. // J. Clin. Oncol. - 2002. - Vol. 20. - P. 1989-1995.

Supplementary files

Supplementary Files

Action

1. JATS XML

Download

Username
Password
Remember me

Forgot password?	Register

Username
Password
Remember me

Forgot password?	Register

Neoadjuvant chemotherapy using taxanes in the combination treatment of non-small cell lung cancer

Full Text

Abstract

Keywords

About the authors

References

Supplementary files

This website uses cookies