Features of Recurrence of Basal Cell Carcinoma of the Scalp



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Abstract

BACKGROUND: Basal cell carcinoma (BCC) is the most common malignant neoplasm in humans. The cause of local recurrence after radical treatment remains unknown.

AIM: The work aimed to identify prognostically significant factors for the development of recurrent basal cell carcinoma of the skin.

METHODS: We analyzed clinicopathological data from 100 cases of BCC, including 50 cases of newly diagnosed basal cell carcinoma of the scalp and 50 cases with recurrent disease.

RESULTS: The incidence of BCC recurrence on the nose was four times higher compared to other localizations. Recurrence on the nasal skin occurred in 21 cases; in 29 patients, recurrence was observed when BCC was localized on the skin of the scalp (n = 3), auricle (n = 3), frontal (n = 4), periorbital (n = 8), temporal (n = 2), buccal (n = 7), zygomatic (n = 1), and lip areas (n = 1). Recurrence of BCC in the frontal area was detected 24 months after treatment; with a tumor infiltration depth of 15.1–20 mm, recurrence occurred at 36 months; in the multicentric variant of BCC, recurrence was noted at 24 months postoperatively.

CONCLUSION: Diagnostic criteria for BCC recurrence may include localization on the nasal skin, multicentric BCC, BCC originating from skin adnexa, and an infiltration depth of 15.1–20 mm.

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About the authors

Tatiana S. Ermakova

City Clinical Oncology Dispensary, St. Petersburg, Russia

Email: ermakova.ts@mail.ru
ORCID iD: 0000-0002-1899-554X

Oncologist

Russian Federation, St. Petersburg, Russia

Eldar E. Topuzov

City Clinical Oncology Dispensary, St. Petersburg, Russia

Email: eltop@inbox.ru
ORCID iD: 0000-0002-1700-1128
SPIN-code: 1065-4191
Scopus Author ID: 6701351647
ResearcherId: O-9523-2015

MD, Dr. Sci. (Medicine), Professor

Russian Federation, St. Petersburg, Russia

Vladimir A. Ershov

City Clinical Oncology Dispensary, St. Petersburg, Russia

Email: ershov415@gmail.com
ORCID iD: 0000-0002-8641-1489

MD, Dr. Sci. (Medicine)

Russian Federation, St. Petersburg, Russia

Svetlana I. Kutukova

City Clinical Oncology Dispensary, St. Petersburg, Russia

Author for correspondence.
Email: dr.s.kutukova@gmail.com
ORCID iD: 0000-0003-2221-4088
SPIN-code: 6735-6556

MD, Dr. Sci. (Medicine), Professor

Russian Federation, St. Petersburg, Russia

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СМИ зарегистрировано Федеральной службой по надзору в сфере связи, информационных технологий и массовых коммуникаций (Роскомнадзор).
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