Digital technologies in prostate cancer prevention and early diagnosis

Background. Prostate cancer is one of the most common malignant neoplasms in males. The Russian Federation observed the same patterns: the incidence of prostate cancer is steadily growing, without the tendency to decrease. Currently, no effective methods are available for prostate cancer early diagnosis and screening.

Aim. To improve the effectiveness of prostate cancer prevention and early diagnosis with new digital technologies for high-risk cancer group formation

Material and methods. Data from the Cancer Registry population in the “Altai regional cancer center,” Barnaul City was used. The Cancer Registry includes information about 253,000 patients with malignant neoplasms, including 14,482 males suffering from prostate cancer. Based on the targeted prevention method of A.F. Lazarev, “Method for determining the risk of prostate cancer” (Patent 2692987) and “Automated program for early diagnosis of prostate cancer” (certificate of state registration of the computer program No. 2019663514) was developed, which simplifies the stage of forming groups of precancerous high oncorisk and increases prostate cancer detection, as well as develops personalized targeted preventive measures for each patient.

Results. The study formed a group of 328 patients with precancerous high oncorisk for prostate cancer in the Cancer Registry, wherein an in-depth examination revealed 26 patients with prostate cancer, which was 7.9%. Stages I and II were established in 97.8%.

Conclusion. The web application “Automated program for early diagnosis of prostate cancer” allows the group formation of high-risk patients who are a targeted search for prostate cancer. The testing process allows a large number of patients to be examined in a short time. The “automated program for the early diagnosis of prostate cancer” allows a statistically significant increased prostate cancer detection, as well as personalized preventive measure suggestions for each patient.