Мақаланы E-mail арқылы жіберу Effect of nanocluster polyoxometalate {mo72fe30} on morphofunctional state of macrophages in cultures
- Авторлар: Titova S.A.1, Tonkushina M.O.1, Grzhegorzhevskii K.V.1, Danilova I.G.1,2, Pozdina V.A.2, Ulitko M.V.1, Ostroushko A.A.1
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Мекемелер:
- Ural Federal University named after the First President of Russia B. N. Yeltsin
- Institute of Immunology and Physiology, Urals Branch, Russian Academy of Sciences
- Шығарылым: Том 66, № 4 (2024)
- Беттер: 367-379
- Бөлім: Articles
- URL: https://rjonco.com/0041-3771/article/view/669501
- DOI: https://doi.org/10.31857/S0041377124040053
- EDN: https://elibrary.ru/QCQFVM
- ID: 669501
Дәйексөз келтіру
Ашық рұқсат
Рұқсат берілді
Аннотация
The aim of this work was to study the effect of nanocluster polyoxometalate {Mo72Fe30} on the macrophage link of the immune system. In vitro studies of polyoxometalate on macrophage cultures allowed us to evaluate the reaction of immune system cells (in particular, peritonial and alveolar macrophages) to nanoparticles. The analysis of the obtained data allowed to establish that {Mo72Fe30} is not toxic for peritonial and alveolar macrophages, has no significant effect on the morphology of cells, as well as on the activity of α-naphthylacetate esterase. However, it significantly reduces phagocytic activity when cells are cultured with POM, which may indicate possible polarisation of macrophages. The obtained results confirm the possibility of using {Mo72Fe30} in the field of biomedicine.
Негізгі сөздер
Толық мәтін
Авторлар туралы
S. Titova
Ural Federal University named after the First President of Russia B. N. Yeltsin
Хат алмасуға жауапты Автор.
Email: svetattitova12021998@gmail.com
Ресей, Ekaterinburg
M. Tonkushina
Ural Federal University named after the First President of Russia B. N. Yeltsin
Email: svetattitova12021998@gmail.com
Ресей, Ekaterinburg
K. Grzhegorzhevskii
Ural Federal University named after the First President of Russia B. N. Yeltsin
Email: svetattitova12021998@gmail.com
Ресей, Ekaterinburg
I. Danilova
Ural Federal University named after the First President of Russia B. N. Yeltsin; Institute of Immunology and Physiology, Urals Branch, Russian Academy of Sciences
Email: svetattitova12021998@gmail.com
Ресей, Ekaterinburg; Ekaterinburg
V. Pozdina
Institute of Immunology and Physiology, Urals Branch, Russian Academy of Sciences
Email: svetattitova12021998@gmail.com
Ресей, Ekaterinburg
M. Ulitko
Ural Federal University named after the First President of Russia B. N. Yeltsin
Email: svetattitova12021998@gmail.com
Ресей, Ekaterinburg
A. Ostroushko
Ural Federal University named after the First President of Russia B. N. Yeltsin
Email: svetattitova12021998@gmail.com
Ресей, Ekaterinburg
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