The mutagenicity and carcinogenicity of pesticides and hazards for human health: A systematic review

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Abstract

The article presents concise review of data obtained during last years at studying mutagenic and carcinogenic activity of pesticides in test-systems in vitro and in vivo Also, are covered the results of epidemiological surveys carried out in Russia and abroad related to discovery of association of effect of pesticides and development of oncological diseases in workers involved into agricultural manufacturing and in population of rural regions. The publications search was implemented using databases of Scopus, Medline, Google Scholar, RINTC. The issues are discussed concerning evaluation of mutagenic characteristics of effecting substances and preparative forms ofpesticides, application of short-term tests for evaluating carcinogenicity, possible synergy effects in case of combination of two and more effecting substances of various pesticide preparations.

About the authors

N. A. Ilyushina

F.F. Erisman Federal Research Center of Hygiene

Author for correspondence.
Email: ilyushina-na@mail.ru
Russian Federation

O. V. Egorova

F.F. Erisman Federal Research Center of Hygiene

Email: noemail@neicon.ru
Russian Federation

G. V. Masal’Tsev

F.F. Erisman Federal Research Center of Hygiene

Email: noemail@neicon.ru
Russian Federation

N. S. Averyanova

F.F. Erisman Federal Research Center of Hygiene

Email: noemail@neicon.ru
Russian Federation

Yu. A. Revazova

F.F. Erisman Federal Research Center of Hygiene

Email: noemail@neicon.ru
Russian Federation

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Copyright (c) 2020 Ilyushina N.A., Egorova O.V., Masal’Tsev G.V., Averyanova N.S., Revazova Y.A.

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