THE ROLE OF INTRAUTERINE INFECTION IN PERINATAL MORTALITY

Рre-natal (congenital) infections - an infectious disease of the fetus and newborn, related to severe pathology, which increases perinatal morbidity and mortality. Objective: to study the role of pre-natal infections in the structure of perinatal mortality (PM) in the Omsk region for 2010-2018. Material and methods. A retrospective analysis of the dynamics and structure of the causes of perinatal mortality was carried out; “Information on medical care for pregnant women, women in labor and women in childbirth” was used (form No. 32) for the analysis. Results. In the Omsk Region, the PM indicator decreased from 14.3‰ in 2010 to 6.7‰ in 2018, which was achieved by reducing the еarly neonatal mortality (from 3.1‰ to 1.9‰) and the stillbirth rate (from 11.2‰ to 4.9‰) for the same years. Еarly neonatal mortality was 11.7% in the group of full-term fetuses from infectious diseases specific to the perinatal period (P35-39), 6.5% - in premature infants with a gestational age of 22-27 weeks, 9.5% - in the group of premature infants with a gestation period of 28-37 weeks. Discussion. The problem of intrauterine infections is relevant, which is due to the high infection rate of women of reproductive age, leading to infertility, low index of their health, and the lack of clear algorithms for diagnosis, treatment and prevention of this disease. Conclusion. Рre-natal infections are the main cause of еarly neonatal mortality in full-term fetuses, accounting for 19.9% of the total number of causes (congenital pneumonia P23 - 8.2%, infectious diseases specific to the perinatal period P35-P39 - 11.7%).

perinatal mortality, intrauterine infections, congenital pneumonia