The incidence of tuberculosis and HIV-infection among adult population in Russia

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Abstract

Introduction. Assessment of dynamics of the overall incidence of both tuberculosis and HIV-infection, without a detailed analysis of its distribution by age, is insufficient to understand the current trends and their forecast from the standpoint of achieving WHO and UNAIDS targets in relation to the elimination of tuberculosis (2035) and HIV-infection (2030).

The purpose of the study: to study the age characteristics of the incidence of tuberculosis and HIV-infection in the adult population of Russia in dynamics for 2010–2019.

Material and methods: retrospective analysis of the incidence of tuberculosis and HIV-infection, and its age structure for 2010–2019.

Results: In Russia, in 2010–2019, the incidence of tuberculosis in the adult population (≥ 18 years) has been steadily decreasing. However, analysis of its distribution by age showed that among young groups (25–44 years) its level was higher and reached the maximum value of 84.6 per 100,000 of population in the group of 35–44 years. In recent years, an increase in the incidence of HIV-infection was observed in Russia, and its highest values were recorded among patients from young age groups (25–44 years).

Limitations of the study. The analysis of the incidence of tuberculosis and HIV infection in the adult population of Russia was carried out both in general for the entire population and in individual age groups for the period from 2010 to 2019, which seemed sufficient to effectively achieve this goal.

Discussion: Retention of high incidence of tuberculosis and an increase in the incidence of HIV-infection among patients aged 25–44 is largely due to widespread prevalence of tuberculosis among patients with HIV-infection. Today in Russia every fourth patient with tuberculosis, both newly diagnosed and among the contingents with TB, is a patient with HIV-infection with manifestations of tuberculosis.

Conclusion: In Russia over the past 10 years, an increase in the number of newly diagnosed HIV-infected patients with TB manifestations, which are included in the structure of both the incidence of HIV infection and TB, has led to an increase in the incidence of HIV infection and a slowdown in the rate of decline in the incidence of TB among young age groups.

Compliance with ethical standards. This study did not require the submission of the conclusion of the biomedical ethics committee or other documents.

Contribution of the authors:
Tsybikova E.B. — concept and design of the research, analysis of statistical data, writing and editing of text.
Gadirova M.E. — collection of materials, analysis of statistical data, writing and editing of text.
The co-authors approved the final version of the article and take responsibility for the integrity of all its parts. 

Acknowledgment. The study had no sponsorship.

Conflict of interest. The authors declare no conflict of interest. 

Received: March 02, 2021
Accepted: April 20, 2021
Published: June 28, 2022

About the authors

Erzheny B. Tsybikova

Central Research Institute for Organization and Informatization of Health Care

Author for correspondence.
Email: erzheny2014@yandex.ru
ORCID iD: 0000-0002-9131-3584

MD, PhD, DSci., Central Research Institute for Organization and Informatization of Health Care, Moscow, 127254, Russian Federation.

e-mail: erzheny2014@yandex.ru

Russian Federation

Mirvari E. Gadirova

Central Research Institute for Organization and Informatization of Health Care

Email: noemail@neicon.ru
ORCID iD: 0000-0002-2625-4864
Russian Federation

References

  1. WHO. End TB strategy. Available at: https://www.who.int/tb/strategy/End_TB_Strategy.pdf
  2. Vasileva I.A., Samoylova G.A., Zimina V.N., Komissarova A.G., Bagdasaryan T.R., Lovacheva O.V. Tuberculosis treatment: past experience, current state and prospects. Tuberkulez i bolezni legkikh. 2013; 90(5): 031–8. (in Russian)
  3. Tuberculosis in adults. Clinical guidelines; 2021. Available at: https://obltub.ru/assets/files/2020/01.20/kr-tuberkulez-u-vzroslyh-2020.pdf (in Russian)
  4. Pokrovskiy V.V. HIV Infection. Clinic, Diagnosis and Treatment [VICh-infektsiya. Klinika, diagnostika i lechenie]. Moscow: Meditsina; 2003. (in Russian)
  5. WHO. Global health sector strategy on HIV 2016-2021. Towards ending AIDS. Available at: https://apps.who.int/iris/handle/10665/246178
  6. UNAIDS Strategy 2016–2021. Available at: https://www.unaids.org/sites/default/files/media_asset/20151027_UNAIDS_PCB37_15_18_EN_rev1.pdf
  7. Voronin E.E. HIV in the Russian Federation. Ural’skiy meditsinskiy zhurnal. 2016; (9): 6–8. (in Russian)
  8. Federal clinical guidelines for the diagnosis and treatment of tuberculosis in patients with HIV infection. Tver’: Triada; 2014. (in Russian)
  9. Tsybikova E.B., Syunyakova D.A. Tuberculosis combined with HIV infection in Russia: current state and prospects. In: Ryazantsev S.V., Rostovskaya T.K., eds. National Demographic Priorities: New Approaches, Trends [Natsional’nye demograficheskie prioritety: novye podkhody, tendentsii]. Moscow: Ekon-Inform; 2019: 154–7. (in Russian)
  10. Guidelines for monitoring and evaluating joint activities to combat TB/HIV. Available at: https://whqlibdoc.who.int/publications/2011/9789244598191_rus.pdf (in Russian)
  11. Lawn S.D., Churchyard G. Epidemiology of HIV-associated tuberculosis. Curr. Opin. HIV AIDS. 2009; 4(4): 325–33. https://doi.org/10.1097/coh.0b013e32832c7d61
  12. Vladimirov A.V., Tsybikova E.B. Structure of death causes in HIV-infected patients by age groups. Sotsial’nye aspekty zdorov’ya naseleniya. 2018; (3): 10. (in Russian)
  13. Tsybikova E.B. Epidemiological indicators of tuberculosis combined with HIV-infection. Sotsial’nye aspekty zdorov’ya naseleniya. 2012; (5): 12. (in Russian)
  14. Ravilon M.K., Korobitsyn A.A. Tuberculosis eradication – a new WHO strategy in the era of Sustainable Development Goals, contribution of the Russian Federation. Tuberkulez i bolezni legkikh. 2016; 94(11): 7–15. (in Russian)
  15. WHO and ECDC report. Tuberculosis surveillance and monitoring report in Europe 2019. Available at: https://www.ecdc.europa.eu/en/publications-data/tuberculosis-surveillance-and-monitoring-europe-2019
  16. Burki T. Surveillance, co-infection, resistance: tuberculosis in Europe. Lancet Infect. Dis. 2011; 11(5): 350–1. https://doi.org/10.1016/s1473-3099(11)70113-x
  17. WHO. HIV-Associated Tuberculosis. Available at: https://www.who.int/tb/publications/global_report/gtbr2017_main_text.pdf
  18. Tsybikova E.B., Vladimirov A.V. The mortality of tuberculosis and HIV-infection in various age gender groups of population in Russia in the beginning of XXI century. Zdravookhranenie Rossiyskoy Federatsii. 2015; 59(5): 4–9. (in Russian)
  19. Panteleev A.M., Ivanov A.K., Vinogradova E.N., Fomenkova N.V., Suprun T.Yu. Lethality analysis in patients with tuberculosis and HIV. Problemy tuberkuleza i bolezney legkikh. 2005; (10): 46–8. (in Russian)
  20. Gandhi N.R., Moll A., Sturm A.W., Pawinski R., Govender T., Lalloo U., et al. Extensively drug-resistant tuberculosis as a cause of death in patients co-infected with tuberculosis and HIV in a rural area of South Africa. Lancet. 2006; 368(9547): 1575–80. https://doi.org/10.1016/s0140-6736(06)69573-1

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