Colorectal cancer: analysis of morbidity and mortality in the Republic of Tatarstan

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Abstract

Introduction. Colorectal cancer is one of the topical cancers, the incidence of which is growing significantly.

Purpose: is analysis of incidence and mortality from colorectal cancer in the Republic of Tatarstan.

Material and methods. The study was conducted using data from official statistical reporting forms, linear regression, cluster analyzes. For statistical data processing there were used MS Excel and Statistica Trial 13.

Results. During the studied period in the Republic of Tatarstan, there has been a tendency towards an increase in the incidence of colon cancer (R2 = 0.98) and cancer of the rectosigmoid junction, rectum and anus (R2 = 0.91). The overall gain in the incidence of colon cancer over 2018 compared to 2014 was 21.6%, an average annual increase of 6.2% (t = 12.5; p = 0.001); cancer of the rectum, rectosigmoid junction and anus — 32.4%, the average annual growth rate — 7.9% (t = 5.53; p = 0.011). Against the background of an increase in morbidity, mortality rates from CRC are relatively stable. The share of CRC in 2018 in the structure of the incidence of the population of the Republic of Tatarstan with cancer was 13.4%, in the structure of mortality — 15%. The conducted cluster analysis made it possible to identify in the territory of the Republic of Tatarstan four clusters which have statistically significant differences between the indicators of colorectal cancer incidence and mortality from it.

Limitations of the study. The analysis of morbidity and mortality from CRC of the population was carried out both for the entire territory of the Republic of Tatarstan and for individual regions, for the period from 2014 to 2018, which seemed sufficient to achieve the set goal.

Conclusion. In modern conditions, CRC is an actual oncological pathology, the share of which in the morbidity structure of the population of the Republic of Tatarstan cancer in 2018 was 13.4%, mortality — 15%. To change the negative trends in morbidity and mortality of the population of the Republic of Tatarstan from CRC, it is necessary to conduct research on the scale of the republic aimed at assessing the impact of various risk factors and early diagnosis of this pathology.

Compliance with ethical standards. This study did not require the submission of a biomedical ethics committee opinion or other documents.

Contribution of the authors:
Yusupova N.Z. — research concept and design, writing the text, editing;
Giniyatullina L.A. — collection and processing of material, writing the text, compilation of the list of literature, statistical data processing.
All authors are responsible for the integrity of all parts of the manuscript and approval of the manuscript final version.

Acknowledgment. The study had no sponsorship.

Conflict of interest. The authors declare no conflict of interest. 

Received: September 22, 2020
Accepted: January 14, 2021
Published: February 28, 2023

About the authors

Nailya Z. Yusupova

Kazan State Medical Academy — Branch Campus of the Russian Medical Academy of Continuous Professional Education,

Author for correspondence.
Email: nelya321@mail.ru
ORCID iD: 0000-0002-8052-2620

MD, PhD, DSci. Head of Department of hygiene of the Kazan State Medical Academy — Branch Campus of the Russian Medical Academy of Continuous Professional Education, Kazan, 420012, Russian Federation.

e-mail: nelya321@mail.ru

Russian Federation

Liliya A. Giniyatullina

Kazan State Medical Academy — Branch Campus of the Russian Medical Academy of Continuous Professional Education,

Email: noemail@neicon.ru
ORCID iD: 0000-0002-9243-8688
Russian Federation

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