Varianty rezektsii pecheni pri zlokachestvennykh opukholyakh



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Abstract

The paper analyzes the results of surgical treatment in 85 patients with malignant liver tumors. According to the nature of a tumor process, all the patients were divided into two group: 1) 16 (18.8%) patients with hepatocellular carcinoma (HCC) and 2) 69 (81.9%) with colorectal cancer liver metastases (CCLM). The staging distribution of patients was as follows: 1) (TNM) 7 (43.7%) patients with Stages II-III and 9 (56.3%) with Stage IVA; 2) mTNM) 1 (1.4%) patient with Stage I, 12 (17.4%) with Stage II, 15 (21.7%) with Stage III, and 31 (44.9%) with Stage IVA, and 10 (14.5%) with Stage IVB. Choice of a resection mode was determined by the clinical and pathological factors of a tumor and the functional reserve of the liver. Extended hemihepatectomy (EHH) was carried out in 6 patients with HCC; hemihepatectomy (HH) in 2; bisegmentectomy in 2, and segmentectomy in 1; nonanatomic resections in 4; a combination of anatomic and non-anatomic resections in 1. Fifty-three (77%) and 7 (10%) patients with CCLM underwent anatomic and anatomic resections, respectively; a combination of both resection modes was performed in 9 (13%0 cases. According to the volume of anatomic resection, the patient distribution was as follows: EHH in 15 (28%) patients, HH in 21 (40%), bisegmentectomy in 7 (15%), and segmentectomy in 10 (19%). The preoperative risk for hepatic failure was assessed by ultrasonography and a methacetin breath test. No extensive resection was made if the hepatectomy index was less 3.8%. Postoperative complications occurred in 4 patients with HCC. Post-CCLM mortality was 4.3%. In patients with HCC, 5-year survival was 48%; in those with CCLM, 5-year overall and relapse-free survival were 35.1 and 22.4%, respectively.

References

  1. Барсуков Ю. А., Алиев В. А., Черкес В. Л. и др. // Вестн. РОНЦ им. Н. Н. Блохина РАМН. - 2007. - Т. 18, № 3. - С. 15-18.
  2. Abdalla E. K. // Nat. Clin. Pract. Gastroenterol. Hepatol. - 2006. - Vol. 3. - P. 18-19.
  3. Alberts R. S., Gores G. J., Kim G. P. et al. // Mayo Clin. Proc. - 2007. - Vol. 82. - P. 628-637.
  4. Capassotti L., Muratore A., Amisano M. et al. //Eur. J Surg. Oncol. - 2005. - Vol. 31. - P. 986-993.
  5. Ferrero A., Polastri R., Muratore A. et al. // J. Hepatobil. Pancreat. Surg. - 2004. - Vol. 11. - P. 92-96.
  6. Hamady Z. Z., Cameron I. C., Wyatt J. et al. // Eur. J. Surg. Oncol. - 2006. - Vol. 32. - P. 557-563/
  7. Hasegawa K., Kokudo N., Imamura H. et al. // Ann. Surg. - 2005. - Vol. 242. - P. 252-259.
  8. Ikai I., Itai Y., Okita K. et al. // Hepatol. Res. - 2004. - Vol. 28. - P. 21-29.
  9. Imamura H., Seyama Y., Kokudo N. et al. //Arch. Surg. - 2003. - Vol. 138. - P. 1198-1206.
  10. Makuuchi M., Sano K. // Liver Transplant. - 2004. - Vol. 10. - Suppl. 1. - P. 46-52.
  11. Pawlik T. M., Scoggins C. R., Zorzi D. // Ann. Surg. - 2005. - Vol. 241. - P. 715-722.
  12. Pawlik T. M., Schulick R. D., Choti M. A. // Oncologist. - 2008. - Vol. 13. - P. 1-64.
  13. Portolani N., Coniglio A., Chidoni S. et al. // Ann. Surg. - 2006. - Vol. 243. - P. 229-235.
  14. Taura K., Ikai I., Hatano E. et al. // Ann. Surg. - 2006. - Vol. 244. - P. 265-273.
  15. The S. H., Christein J., Donohue J. et al. // J. Gastrointest. Surg. - 2005. - Vol. 9. - P. 1207-1215.
  16. Welsh F. K., Tekkis P. P., O'Rourke T. et al. // Surg. Oncol. - 2008. - Vol. 17. - P. 3-13.
  17. Zorzi D., Mullen S. T., Abdalla E. K. et al. // J. Gastrointest. Surg. - 2006. - Vol. 10. - P. 86-94.

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СМИ зарегистрировано Федеральной службой по надзору в сфере связи, информационных технологий и массовых коммуникаций (Роскомнадзор).
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