CLINICAL AND MORPHOLOGICAL ASPECTS OF EARLY GASTRIC CANCER AND ASSESSMENT OF PROGNOSTIC FACTORS OF LYMPHOGENIC METASTASIS. (LITERATURE REVIEW)

Abstract

To determine the strategy of treatment of EGC in the world today indications for endoscopic resection, proposed by JGCA, is being used. These indications are presented by a number of morphological factors of the EGC, which are correlate with a low level of lymphogenic metastasis. Not all of the medical centers think these indications are safe. There are publications that question the value of these morphological factors, as well as the heterogeneity of the assessment. Also, in addition to the generally recognized indications for ER JGCA, the researchers proposed other algorithms for the selection of EGS patients with low risk of metastasis to perform ER. These methods were developed using regional standards for different ethnic groups and based on different prognostic parameters. In our review, publications in well-known medical journals in English found through computer search were investigated to study the ways of measuring morphological factors and the safety of jgca readings to ER. The search included such terms as “early gastric cancer”, “prognostic factors”,” lymphogenic metastasis”,” endoscopic resection of the PANCREAS “and “absolute and extended indications for endoscopic resection”. The review includs 60 original studies and meta-analyses. In the original studies, the correlation of demographic and morphological characteristics of the tumor and metastatic process were studied, the variants and methods of evaluation of morphological factors were investigated. The meta-analyses researched the correlation between ER and BREAST surgery, compared the level of safety of absolute and relative criteria of endoscopic resection.

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About the authors

Valeria V. Mochalnikova

N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of Russia

Email: Mochalnikova70@yandex.ru
pathologist, N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of Russia, 115478, Moscow, Russian Federation 115478, Moscow, Russian Federation

A. G Perevochsikov

N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of Russia

115478, Moscow, Russian Federation

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