Giant condiloma of Bushke–Löwenstein: a clinical case

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Giant condyloma Buschke-Levenshtein is a large, exophytic, slow-growing, benign, warty lesion of the anogenital region. The cause of this pathology is infection with the human papillomavirus, mainly of the 6th or 11th type. The pathogenesis of giant genital warts is not well understood, and it is often considered an intermediate link between acute warts and squamous cell carcinoma. The frequency of occurrence in the general population is about 0.1%, which indicates the rarity of this pathology. The giant condyloma Buschke-Löwenstein was first described by the authors Buschke and Löwenstein in 1925. Currently, the literature contains descriptions of mostly single observations of patients with this pathology. The main method of treatment for giant condyloma Buschke-Levenshtein is surgical, the task of which is a wide excision of the tumor within healthy tissues. We present a clinical observation of a patient with a giant condyloma Buschke-Levenshtein. a 36-year-old patient underwent surgical treatment - removal of a large perineal tumor. At the time of surgery, the size of the tumor was about 25 × 15 cm. The patient underwent surgical treatment without complications, healing by primary intention. Within six months after the operation, no recurrence of the disease was detected. Thus, surgical treatment of such tumors is the only method that can count on the patient being cured.

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About the authors

Konstantin V. Menshikov

Bashkir State Medical University

Author for correspondence.

MD, PhD, oncologist of the Department of Chemotherapy of the Republican Clinical Oncological Dispensary, 450054, Ufa, Russian Federation, Associate Professor of the Department of Oncology with courses oncology and pathological anatomy, Bashkir State Medical University, 450008, Ufa, Russian Federation

Russian Federation, 450008, Ufa

O. N. Lipatov

Bashkir State Medical University

Russian Federation, 450008, Ufa

S. F. Nasyrova

Bashkir State Medical University

Russian Federation, 450008, Ufa


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Supplementary files

Supplementary Files
1. Fig. 1. Swelling of the perineum with the transition to the perianal region. Postoperative scars are visible as a result of previous attempts to remove the tumor

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2. Fig. 2. Type of the operating wound. The wound area is more than 200 cm2

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3. Fig. 3. A – type of postoperative wound on the 4th day after surgery, healing by primary intention, skin flaps are viable, no necrosis. B – view two months after surgery, moderate swelling of the labia majora with a tendency to resolve. No relapse was found

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4. Fig. 4. Papillomatosis and distinct acanthosis with pronounced vacuolization of cells. Epidermal processes are thickened and elongated. Staining with hematoxylin and eosin (× 40)

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