Vol 19, No 4 (2014)


Immunosignature - peptide microarray for diagnostic of cancer and other diseases

Chapoval A.I., Legutki J.B., Stafford P., Trebukhov A.V., Johnston S.A., Shoykhet Y.N., Lazarev A.F.


Biomarkers for preclinical diagnosis of cancer is a valuable tool for detection of malignant tumors at early stages in risk groups and screening healthy people, as well as monitoring disease recurrence after treatment of cancer. It is known that antibodies are produced in response to antigens expressed by tumor cells. Accordingly, the presence of specific antibodies in serum can serve as biomarkers of cancer. Recently developed technology - immunosignature is a highly sensitive method of detection of circulating antibodies using peptide microarrays. In the present review we discuss modern methods of antibody detection, as well as describe the principles and applications of immunosignature in research and clinical practice.
Russian Journal of Oncology. 2014;19(4):6-11
pages 6-11 views

Metabolomic research in oncology

Furina R.R.


This paper deals with the questions of the metabolomics research results application in medicine. The central idea metabolomics is to identify the specific biomarkers in a biological sample used in a diagnostics. The volatile organic compounds - metabolites isolated from various tissues and biological fluids (blood, urine, sputum, exhaled air) are considered as biomarkers. The paper also describes main methods of separation and identification of volatile organic compounds (gas chromatography, mass spectrometry, nuclear magnetic resonance spectroscopy) applied in metabolomics. The paper presents some results of laboratory research aimed at the detection of different organs ’ cancer biomarkers. The quality characteristics of the metabolome from a biological patient sample with different pathology are discussed. Special attention is paid to the application of metabolomics possibilities in experimental medicine. The presented material will be of some help in solving the problems of early diagnosis of cancer.
Russian Journal of Oncology. 2014;19(4):12-15
pages 12-15 views

Gastrointestinal stromal tumors of the gastrointestinal tract in the practice of oncology specialized institutions

Anisimova A.V., Vayner I.E., Ilyushin T.V., Kolokol'nikova K.V., Kukva V.A., Nagornaya O.A.
Russian Journal of Oncology. 2014;19(4):16-16
pages 16-16 views

Characteristics of technically complex liver resections

Akhaladze G.G., Chkhikvadze V.D., Grebyenkin E.N., Stanoevich U.S.
Russian Journal of Oncology. 2014;19(4):17-17
pages 17-17 views

Results chemoembolization metastatic colorectal cancer in the liver drug-saturable embosferami combined with systemic chemotherapy

Balakhnin P.V., Zorina E.Y., Dinikin M.S., Khanevich M.D., Manikhas G.M.
Russian Journal of Oncology. 2014;19(4):17-18
pages 17-18 views

Optimal contrast study method for diagnoses of small hypovascular liver metastases during MSCT arterio-hepatography

Balakhnin P.V., Pozdnyakov A.V., Ryllo A.G., Shmelev A.S., Kozyreva K.S.
Russian Journal of Oncology. 2014;19(4):18-18
pages 18-18 views
pages 18-19 views

Prognostic significance of CRP levels in patients with metastatic gastric cancer

Belyak N.P., Kutukova S.I., Antimonik N.Y., Erdniev S.P., Zhukova N.V., Popova N.V., Vaz'yan R.I., Ivanova A.K.
Russian Journal of Oncology. 2014;19(4):19-20
pages 19-20 views
pages 20-20 views

Features of cryoablation Ultrasonic monitoring in patients with liver cancers at various stages of treatment

Vetsheva N.N., Zhavoronkova O.I., Stepanova Y.A., Ionkin D.A., Chzhao A.V.
Russian Journal of Oncology. 2014;19(4):20-21
pages 20-21 views

Metastases of colorectal cancer in the liver. Long -term results analysis of radio frequency thermoablation application

Vishnevskiy V.A., Ionkin D.A., Zhavoronkova O.I., Shurakova A.B., Chzhao A.V.
Russian Journal of Oncology. 2014;19(4):21-21
pages 21-21 views

Multimodal treatment of primary unresectable liver metastases of colorectal cancer: 5 years of observations

Vozdvizhenskiy M.O., Savenkov V.G., Frolov S.A.
Russian Journal of Oncology. 2014;19(4):22-22
pages 22-22 views

Early results of stereotactic radiotherapy in patients with liver metastases

Vorob'yev N.A., Andreev G.I., Kalesnik A.M., Zubatkina I.S., Lubinskiy A.I., Kubasov A.V.
Russian Journal of Oncology. 2014;19(4):22-23
pages 22-23 views

Transplantation in cases of liver neoplasms presence

Granov D.A., Borovik V.V., Zherebtsov F.C., Polikarpov A.A., Maystrenko D.N., Rutkin I.O.
Russian Journal of Oncology. 2014;19(4):23-23
pages 23-23 views

Current approaches to the treatment of patients with colorectal liver metastases: assessment of the immediate and long-term results

Darvin V.V., Onishchenko S.V., Lysak M.M., Krasnov E.A.
Russian Journal of Oncology. 2014;19(4):23-24
pages 23-24 views

Surgical treatment of secondary liver tumors

Zemlyanoy V.P., Filenko B.P., Sigua B.V., Pershina A.S.
Russian Journal of Oncology. 2014;19(4):24-25
pages 24-25 views

The treatment option for patients with resectable metastatic colorectal cancer in the liver

Zorina E.Y., Orlova R.V., Fridman M.K., Khrykov G.N.
Russian Journal of Oncology. 2014;19(4):25-26
pages 25-26 views

Laparoscopic cryoablation of liver malignancies

Ionkin D.A., Chzhao A.V., Kungurtsev S.V.
Russian Journal of Oncology. 2014;19(4):26-27
pages 26-27 views

Method of radiofrequency thermal ablation in the treatment of patients with multiple bilobate metastases from colorectal liver cancer

Kozlov S.V., Kaganov O.I., Tkachyev M.V., Kozlov A.M., Shvets D.S.
Russian Journal of Oncology. 2014;19(4):27-28
pages 27-28 views

Ways to improve the results of extensive liver resections

Kotiv B.N., Dzidzava I.I., Slobodyanik A.V., Smorodskiy A.V., Kashkin D.P., Soldatov S.A.
Russian Journal of Oncology. 2014;19(4):28-28
pages 28-28 views

Treatment results of synchronous liver metastases of gastric cancer and colon

Kotiv B.N., Dzidzava I.I., Slobodyanik A.V., Smorodskiy A.V., Kashkin D.P., Soldatov S.A.
Russian Journal of Oncology. 2014;19(4):29-29
pages 29-29 views

Laparoscopic liver resection (first experience)

Kotiv B.N., Dzidzava I.I., Chuprina A.P., Kashkin D.P.
Russian Journal of Oncology. 2014;19(4):29-30
pages 29-30 views

The role of interventional radiology techniques in the treatment of patients with primary and metastatic liver lesions

Kukanov M.A., Chalaev A.G., Goncharuk M.K.
Russian Journal of Oncology. 2014;19(4):30-30
pages 30-30 views

Cryosurgical equipment. Present and Future

Kungurtsev S.V., Loktev N.P.
Russian Journal of Oncology. 2014;19(4):31-32
pages 31-32 views

Results of thermochemotherapy in patients with metastasis of colorectal cancer in the liver

Kurpeshev O.K., Florovskaya N.Y., Lebedeva T.V.
Russian Journal of Oncology. 2014;19(4):32-32
pages 32-32 views

Blood supply endovascular features of malignant soft tissue tumors

Manikhas G.M., Khanevich M.D., Vashkurov S.M., Kukanov M.A., Chalaev A.G., Goncharuk M.K., Khazov A.V.
Russian Journal of Oncology. 2014;19(4):32-33
pages 32-33 views

Modern aspects of the treatment of patients with cholangitis in malignant tumors of hepatopancreatobiliary zone

Melkonyan G.G., Mumladze R.B., Chechenin G.M., Barinov Y.V., Lebedev S.S.
Russian Journal of Oncology. 2014;19(4):33-34
pages 33-34 views

Epidemiology of liver cancer

Merabishvili V.M., Merabishvili E.N., Chepik O.F.
Russian Journal of Oncology. 2014;19(4):34-35
pages 34-35 views

Dynamics observed and relative survival of patients with liver cancer at the population level, according to the histological structure

Merabishvili V.M., Chepik O.F., Merabishvili E.N.
Russian Journal of Oncology. 2014;19(4):35-36
pages 35-36 views

Low temperature treatment of liver tumors

Merzlikin N.V., Al'perovich B.I., Salo V.N., Klinovitskiy I.Y., Saenko D.S.
Russian Journal of Oncology. 2014;19(4):36-37
pages 36-37 views

Thermophysical modeling application in liver cryosurgery

Morozova N.V., Ponomaryev D.E., Pushkaryev A.V., Tsyganov D.I.
Russian Journal of Oncology. 2014;19(4):37-37
pages 37-37 views

Multidisciplinary approach and minimally invasive technologies in the treatment of primary and metastatic liver cancer

Moshurov I.P., Mikhailov A.A., Fonshteyn M.S., Ol'shanskiy M.S., Letnikov B.A., Ninikashvili L.V., Sukhochev E.N., Makarova E.D.
Russian Journal of Oncology. 2014;19(4):37-38
pages 37-38 views

Complications of antegrade stenting interventions on the bile ducts in patients with cancer

Mumldaze R.B., Barinov Y.V., Chechenin G.M., Lebedev S.S., Melkonyan G.G.
Russian Journal of Oncology. 2014;19(4):38-39
pages 38-39 views

Surgical treatment of hepatocellular carcinoma on a background of cirrhosis

Patyutko Y.I., Kotel'nikov A.G., Sagaydak I.V., Kudashkin N.E., Gakhramanov A.D., Moroz E.A., Chay I.
Russian Journal of Oncology. 2014;19(4):39-40
pages 39-40 views

Endovascular procedures in the treatment of patients with unresectable colorectal cancer metastases to the liver

Polikarpov A.A., Tarazov P.G., Granov D.A., Polysalov V.N.
Russian Journal of Oncology. 2014;19(4):40-41
pages 40-41 views
pages 41-42 views

Perfusion computed tomography imaging of metastatic pancreatic cancer in the liver

Rozengauz E.V., Nesterov D.V.
Russian Journal of Oncology. 2014;19(4):42-42
pages 42-42 views

The first experience of liver resection in situ split type in patient with bilobate metastatic colorectal cancer on the background of perioperative chemotherapy

Sidorov D.V., Lozhkin M.V., Grishin N.A., Petrov L.O., Troitskiy A.A.
Russian Journal of Oncology. 2014;19(4):42-43
pages 42-43 views

Features and the results of parenchyma water-jet dissection technique during anatomical liver resection of colorectal cancer metastases

Sidorov D.V., Lozhkin M.V., Grishin N.A., Petrov L.O., Troitskiy A.A.
Russian Journal of Oncology. 2014;19(4):43-44
pages 43-44 views

Radiofrequency ablation in combination with himiembolizatsiey hepatic artery in the treatment of hepatic malignancies

Skupchenko A.V., Lysenko A.V., Korolyev D.G., Skobeltsov D.A., Rassudishkin A.S.
Russian Journal of Oncology. 2014;19(4):44-45
pages 44-45 views

Surgical Management of liver metastases in patients with locally advanced rectal cancer

Solov’yev I.A., Vasilchenko M.V., Lychyev A.B., Kolunov A.V., Navmatulya A.V., Savchenko D.K.
Russian Journal of Oncology. 2014;19(4):45-45
pages 45-45 views

Transdermal transhepatic drainage of bile duct capabilities in tumours of hepatopancreatoduodenal zone with secondary liver lesions in older age group patients

Solov’yev I.A., Dymnikov D.A., Savchenko D.K., Vasilchenko M.V.
Russian Journal of Oncology. 2014;19(4):45-46
pages 45-46 views

Current treatment options for colorectal cancer metastasis in liver

Strizhakov G.N., Maksimov M.O.
Russian Journal of Oncology. 2014;19(4):46-47
pages 46-47 views

Surgical treatment of patients with complicated colorectal cancer stage IV in a multidisciplinary hospital

Ten O.A., Surov D.A., Babkov O.V., Solov’yev I.A., Bezmozgin B.G., Tyagun V.S.
Russian Journal of Oncology. 2014;19(4):47-48
pages 47-48 views

Transdermal endobiliary intervention in the treatment of obstructive jaundice of tumor genesis

Tibilov A.M., Baymatov M.S., Kul’chiev A.A., Morozov A.A., Tigiev S.V., Tavitova A.G.
Russian Journal of Oncology. 2014;19(4):48-48
pages 48-48 views

Differentiated approach to the treatment of patients with metastatic colorectal cancer with liver metastases

Fridman M.K., Zorina E.Y., Khrykov G.N., Klimov E.V.
Russian Journal of Oncology. 2014;19(4):48-49
pages 48-49 views

Hepatic artery chemoembolization by drug-saturated embosphere in the treatment of patients with primary and metastatic liver tumours

Khanevich M.D., Kukanov M.A., Chalaev A.G., Dinikin M.S., Fadeev R.V., Zorina E.Y.
Russian Journal of Oncology. 2014;19(4):49-50
pages 49-50 views

Cryogenic treatment after radical operations on liver

Khanevich M.D., Manikhas G.M., Vashkurov S.M., Anisimova A.V., Dinikin M.S., Khazov A.V., Musatov K.Y., Fadeev R.V., Pechkurov A.M.
Russian Journal of Oncology. 2014;19(4):50-51
pages 50-51 views

Combined treatment of metastatic colorectal cancer in the liver with the application of cryosurgery

Khanevich M.D., Manikhas G.M., Dinikin M.S., Fadeev R.V.
Russian Journal of Oncology. 2014;19(4):51-51
pages 51-51 views

The immediate results of ALPPS procedures in patients with extensive liver metastases

Chaychenko D.V., Nadvikova E.A., Vazhenin A.V., Privalov A.V.
Russian Journal of Oncology. 2014;19(4):51-52
pages 51-52 views

Results of cryoablation application in primary and metastatic liver cancer

Chzhao A.V., Ionkin D.A., Zhavoronkova O.I., Vetsheva N.N., Shurakova A.B., Kungurtsev S.V.
Russian Journal of Oncology. 2014;19(4):52-53
pages 52-53 views

A combination of local destruction methods in primary and metastatic liver cancer

Chzhao A.V., Ionkin D.A., Zhavoronkova O.I., Shurakova A.B., Kungurtsev S.V.
Russian Journal of Oncology. 2014;19(4):53-54
pages 53-54 views

Microwave and radiofrequency ablation in the treatment of patients with primary and metastatic liver cancer

Shabunin A.V., Bedin V.V., Grekov D.N., Tavobilov M.M., Drozdov P.A.
Russian Journal of Oncology. 2014;19(4):54-55
pages 54-55 views

Experience of surgical treatment of metastatic colorectal cancer in the liver

Shostka K.G., Mulendeev S.V., Pavlenko A.N., Roman L.D.
Russian Journal of Oncology. 2014;19(4):55-55
pages 55-55 views

Application of MRI as a method of assessing the completeness of liver malignancies radiofrequency ablation

Shurakova A.B., Ionkin D.A.
Russian Journal of Oncology. 2014;19(4):55-56
pages 55-56 views

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